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Table 3 Individual treatment results

From: Definitive radiotherapy and Single-Agent radiosensitizing Ifosfamide in Patients with localized, irresectable Soft Tissue Sarcoma: A retrospective analysis

Histology

Localisation

Stage/Grade

Maximal diameter

Initial - before RT

Irradiation dose

Total ifo dose

Toxicity ≥ °III

Local control (Mo)

Overall survival (Mo)

Primary RTCHX

Leiomyos.

HN

T2 G3

8 cm

70.0 Gy

7.5 g/m2

Skin toxicity °III

72

72 AWOD

PNET

Trunk

T2 G3

11 cm

60.0 Gy

15 g/m2

 

9

9 DOD

Anaplastic S.

Trunk

T2 G3

9 cm

60.0 Gy

HF + HT

10 g/m2

 

124

124 AWOD

Angios.

Trunk

T2 G2

8 cm

55.6 Gy

5 g/m2

Interruption (abscess)

106

106 AWOD

Chondros.

Trunk

T2 G2

13 cm

66.0 Gy

10 g/m2

Leucopenia

21 LF

30 DOD

Synovials.

Trunk

T2 G2

25 cm

50.0 Gy

7.5 g/m2

Death during therapy

1

1 DOD

Pleomorphic S.

Trunk

T2 G3

11 cm

70.2 Gy

10 g/m2

Skin toxicity °III

6 LF

10 DOD

RTCHX after R2-resection

Leiomyos.

Trunk

T2 G3

15 cm - 4 cm

66.0 Gy

HF + HT

10 g/m2

 

26

26 DOD

Synovials.

Trunk

T2 G3

9 cm - 3 cm

50.4 Gy

15 g/m2

 

13

13 DOD

Rhabdomyos.

HN

T2 G3

6 cm - 4 cm

72.6 Gy

15 g/m2

Leuco- penia °IV

5

5 DOD

Leiomyos.

Trunk

T2 G3

11 cm

59.6 Gy

15 g/m2

 

4

4 DOD

  1. Abbreviations:
  2. AWOD - Alive without disease
  3. DOD - Dead of disease
  4. HF - Hyperfractionation
  5. HN - Head and neck
  6. HT - Hyperthermia
  7. Ifo - Ifosfamide
  8. LF - Local failure
  9. Mo - Months
  10. PNET - Peripheral neuroectodermal tumor
  11. RT - Radiotherapy
  12. RTCHX - Radiochemotherapy