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Table 2 Univariate analysis of five-year disease-free survival (DFS), local recurrence-free survival (LRFS), regional recurrence-free survival (RRFS), distant metastasis-free survival (DMFS) rate, and overall survival (OS) rate

From: Clinical outcomes for T1-2N0-1 oral tongue cancer patients underwent surgery with and without postoperative radiotherapy

 

5-year DFS

5-year LRFS

5-year RRFS

5-year DMFS

5-year OS

 

(%)

p value

(%)

p value

(%)

p value

(%)

p value

(%)

p value

Age (year)

 

0.233

 

0.239

 

0.712

 

0.312

 

0.789

   < 55

84

 

97

 

84

 

89

 

84

 

   ≥ 55

77

 

87

 

78

 

93

 

77

 

Performance

 

0.718

 

0.162

 

0.44

 

0.692

 

0.421

   ECOG 0

87

 

100

 

87

 

87

 

87

 

   ECOG 1

77

 

88

 

78

 

94

 

78

 

T classification

 

0.331

 

0.575

 

0.101

 

0.856

 

0.186

   T1

84

 

91

 

85

 

96

 

86

 

   T2

74

 

94

 

73

 

83

 

71

 

N classification

 

0.725

 

0.963

 

0.52

 

0.856

 

0.186

   N0

81

 

92

 

82

 

91

 

83

 

   N1

79

 

93

 

79

 

92

 

67

 

Stage

 

0.568

 

0.685

 

0.218

 

0.228

 

0.151

   I

85

 

90

 

86

 

96

 

87

 

   II

72

 

96

 

72

 

82

 

73

 

   III

79

 

93

 

79

 

92

 

67

 

Grade

 

0.005

 

0.015

 

0.013

 

0.024

 

0.001

   Well

88

 

95

 

89

 

96

 

91

 

   Moderate-poor

69

 

86

 

69

 

84

 

65

 

Invasion depth (cm)

 

0.018

 

0.166

 

0.008

 

0.201

 

0.023

   ≤ 0.5

92

 

98

 

92

 

96

 

92

 

   > 0.5

66

 

83

 

66

 

87

 

66

 

Resection margin

 

0.186

 

0.624

 

0.081

 

0.292

 

0.360

   Negative

84

 

92

 

86

 

94

 

84

 

   Close (< 0.5 cm) or positive

65

 

89

 

62

 

86

 

67

 

Lymphovascular invasion

 

0.358

 

0.686

 

0.292

 

0.043

 

0.586

   Yes

67

 

100

 

67

 

67

 

50

 

   No

81

 

91

 

82

 

93

 

82

 

Perineural invasion

 

0.662

 

0.135

 

0.598

 

0.602

 

0.283

   Yes

67

 

67

 

50

 

100

 

67

 

   No

81

 

93

 

82

 

91

 

81

 

Radiotherapy

 

0.475

 

0.161

 

0.775

 

0.548

 

0.647

   Yes

86

 

100

 

86

 

86

 

86

 

   No

79

 

90

 

80

 

93

 

80

 

Operation of primary site

 

0.284

 

0.608

 

0.775

 

0.548

 

0.647

   Simple excision

74

 

83

 

74

 

100

 

81

 

   Hemiglossectomy

78

 

82

 

80

 

89

 

81

 

   Wide excision

100

 

100

 

100

 

100

 

100

 

Neck dissection

 

0.534

 

0.556

 

0.518

 

0.898

 

0.882

   Yes

82

 

93

 

83

 

92

 

81

 

   No

76

 

88

 

75

 

90

 

80

 
  1. Abbreviations : ECOG = Eastern Cooperative Oncology Group