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Table 2 The parameters of predicted helical tomotherapy plan within mean 30 Gy to normal liver of hepatocellular carcinoma compared with selected published series.

From: Comparison of coplanar and noncoplanar intensity-modulated radiation therapy and helical tomotherapy for hepatocellular carcinoma

Published series Modality Mean Tumor dose (Gy)
/fraction size (Gy)
V30 (%) Suggested mean dose (Gy) of normal liver under radiotherapy
Dawson et al. [28] 3DCRT 52.5/1.5-1.65   30 Gy10
Kim et al. [29] 3DCRT 54/2   30 Gy
Cheng et al. [45] 3DCRT 50/1.8-2 42%  
Liang et al. [40] 3DCRT 50/4-6 35% 28 Gy10
Yamada et al. [44] 3DCRT 57/2 40%  
IMRT Coplanar IMRT 50.4/1.8 21% 20 Gy
IMRT Noncoplanar IMRT 50.4/1.8 17% 20 Gy
HT Tomotherapy 50.4/1.8 17% 20 Gy
  1. Abbreviations: 3DCRT = Three-dimensional conformal radiotherapy; HT = Helical tomotherapy; V30 = percent volume of normal liver with radiation dose more than 30 Gy; X Gy10 = a biologic effective dose (BED) of X Gy10 as the α/β ratio = 10 in daily fraction of 2 Gy; OARs = Organs at risk.