Comparison of coplanar and noncoplanar intensity-modulated radiation therapy and helical tomotherapy for hepatocellular carcinoma

Table 2 The parameters of predicted helical tomotherapy plan within mean 30 Gy to normal liver of hepatocellular carcinoma compared with selected published series.

Published series	Modality	Mean Tumor dose (Gy) /fraction size (Gy)	V30 (%)	Suggested mean dose (Gy) of normal liver under radiotherapy
Dawson et al. [28]	3DCRT	52.5/1.5-1.65		30 Gy₁₀
Kim et al. [29]	3DCRT	54/2		30 Gy
Cheng et al. [45]	3DCRT	50/1.8-2	42%
Liang et al. [40]	3DCRT	50/4-6	35%	28 Gy₁₀
Yamada et al. [44]	3DCRT	57/2	40%
IMRT	Coplanar IMRT	50.4/1.8	21%	20 Gy
IMRT	Noncoplanar IMRT	50.4/1.8	17%	20 Gy
HT	Tomotherapy	50.4/1.8	17%	20 Gy

Abbreviations: 3DCRT = Three-dimensional conformal radiotherapy; HT = Helical tomotherapy; V30 = percent volume of normal liver with radiation dose more than 30 Gy; X Gy₁₀ = a biologic effective dose (BED) of X Gy₁₀ as the α/β ratio = 10 in daily fraction of 2 Gy; OARs = Organs at risk.

ISSN: 1748-717X