Skip to main content

Table 1 ED50 values for radiation and gossypol in human leukemic cells

From: AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis

 

U937

Jurkat T

Radiation (Gy)

21.6

12.6

AT-101 (μM)

2.4

1.9

(±)-Gossypol (μM)

5.8

2.4

  1. Values are derived from full dose-response curves for each stimulus at t = 24 h; data are mean values from 2 independent experiments.
Back to article page

Radiation Oncology

ISSN: 1748-717X

Contact us