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Figure 2 | Radiation Oncology

Figure 2

From: AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis

Figure 2

Dose-dependent induction of apoptosis by radiation (A, B) and AT-101 (C, D) in human leukemic U937 (A, C) and Jurkat T cells (B, D). Apoptosis was quantified by FACScan analysis at t = 24 h after treatment. Data are presented as mean values (± SD) from 3 independent experiments. Inserts in C and D show the time-dependency of AT-101.

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Radiation Oncology

ISSN: 1748-717X

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