Table 4 Impact of patient-related and dose-volume-related factors on quality of life score changes

bowel function score

AUC-R≥50%

13 vs. 16

3 vs. 8

1 vs. 4†

R70≥25%

15 vs. 16

4 vs. 12*

2 vs. 8*

coronary heart disease

17 vs. 14

8 vs. 4†

3 vs. 3

stroke in past history

10 vs. 15

3 vs. 5

7 vs. 3†

chronic renal failure

30 vs. 15

15 vs. 5

11 vs. 3†

irritative function

AUC-R≥50%

16 vs. 20

4 vs. 8

1 vs. 5†

R70≥25%

18 vs. 18

5 vs. 13†

2 vs. 9†

chronic renal failure

41 vs. 18

8 vs. 6

12 vs. 3†

incontinence function

AUC-R≥50%

11 vs. 8

0 vs. 8†

2 vs. 6

R70≥25%

10 vs. 8

3 vs. 12†

3 vs. 9†

rectal bleeding

PTV≥300 cm³

4 vs. 4

2 vs. 2

4 vs. 0*

NHT

4 vs. 4

3 vs. 2

0 vs. 4*

coronary heart disease

6 vs. 3

5 vs. 1†

4 vs. 2

haemorrhoids

12 vs. 4

7 vs. 2†

9 vs. 3†

stroke in past history

0 vs. 4

0 vs. 2

10 vs. 3*

bowel bother score

R70≥25%

19 vs. 27

8 vs. 22*

5 vs. 15*

stroke in past history

9 vs. 20†

2 vs. 10

8 vs. 7

chronic renal failure

37 vs. 19

11 vs. 10

21 vs. 6*

irritative bother

AUC-R≥50%

10 vs.15†

8 vs. 11

6 vs. 7

R70≥25%

22 vs. 31

10 vs. 26*

6 vs.16

chronic renal failure

48 vs. 23

15 vs. 12

22 vs. 7*

incontinence bother

R70≥25%

11 vs. 21

9 vs. 16

5 vs. 14†

rectal bleeding bother

PTV≥300 cm³

4 vs. 6

2 vs. 4

5 vs. 0†

coronary heart disease

7 vs. 3

5 vs. 2*

3 vs. 4