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Figure 1 | Radiation Oncology

Figure 1

From: Constitutive gene expression profile segregates toxicity in locally advanced breast cancer patients treated with high-dose hyperfractionated radical radiotherapy

Figure 1

Experimental design. RNA from lymphocytes treated with 0 and 2 Gy dose of radiation were compared against a human universal RNA. SAM analyses were performed to disclose significant regulated genes in these two ways. In order to explore genes modulated by radiation, a two-class paired test was performed using SAM. To discriminate genes that could be significantly associated with RT toxicity, non-supervised hierarchical clustering, in MeV, was used to visualize the whole set of significant genes modulated before and after X-ray exposure in patients with and without acute/late toxicity.

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Radiation Oncology

ISSN: 1748-717X

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