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Table 2 A comparison of doses to the heart and ipsilateral lung dosimetry from the MammoSite catheter and external beam radiotherapy using the radiobiologically adjusted dosimetric parameters.

From: Dose volume histogram analysis of normal structures associated with accelerated partial breast irradiation delivered by high dose rate brachytherapy and comparison with whole breast external beam radiotherapy fields

MammoSite (34 Gy/10#/1 week) External Beam (50 Gy/25#/5 weeks) p-value
Mean Range Mean Range  
Lung     
V23.5 7 cc 0–20.4 cc V30 86.7 cc 31.5–184 cc p = 0.05*
V23.5 0.7% 0–1.5% V30 8.3% 2.3–19.9% p = 0.03*
V16.5 23.6 cc 0–57.9 cc V20 105 cc 46.1–205 cc p = 0.06
V16.5 2.3% 0–4.2% V20 10% 3.3–22.2% p = 0.03*
V9 98.1 cc 0–201.7 cc V10 133.6 cc 67.8–235 cc p = 0.48
V9 9.4% 0–13.3% V10 12.8% 4.9–25.4% p = 0.26
Heart     
V16.5 1.2 cc 0–5.2 cc V20 15.7 cc 0–23.9 cc p = 0.009*
V16.5 0.3% 0–1.2% V20 3.7% 0–5.3% p = 0.01*
V9 15.9 cc 2.1–47.4 cc V10 22.9 cc 0.3–39.0 cc p = 0.34
V9 3.7% 0.5–10.5% V10 5.4% 0.1–8.7% p = 0.35
V4.5 105.7 cc 64.5–173.5 cc V5 41.47 cc 3.1–82.3 cc p = 0.001*
V4.5 25.0% 15.1–38.5% V5 9.6% 0.8–18.3% p = 0.002*
  1. * represents a statistically significant p-value