Table 2 A comparison of doses to the heart and ipsilateral lung dosimetry from the MammoSite catheter and external beam radiotherapy using the radiobiologically adjusted dosimetric parameters.
MammoSite (34 Gy/10#/1 week) | External Beam (50 Gy/25#/5 weeks) | p-value | ||
|---|---|---|---|---|
Mean | Range | Mean | Range | Â |
Lung | Â | Â | Â | Â |
V23.5 7 cc | 0–20.4 cc | V30 86.7 cc | 31.5–184 cc | p = 0.05* |
V23.5 0.7% | 0–1.5% | V30 8.3% | 2.3–19.9% | p = 0.03* |
V16.5 23.6 cc | 0–57.9 cc | V20 105 cc | 46.1–205 cc | p = 0.06 |
V16.5 2.3% | 0–4.2% | V20 10% | 3.3–22.2% | p = 0.03* |
V9 98.1 cc | 0–201.7 cc | V10 133.6 cc | 67.8–235 cc | p = 0.48 |
V9 9.4% | 0–13.3% | V10 12.8% | 4.9–25.4% | p = 0.26 |
Heart | Â | Â | Â | Â |
V16.5 1.2 cc | 0–5.2 cc | V20 15.7 cc | 0–23.9 cc | p = 0.009* |
V16.5 0.3% | 0–1.2% | V20 3.7% | 0–5.3% | p = 0.01* |
V9 15.9 cc | 2.1–47.4 cc | V10 22.9 cc | 0.3–39.0 cc | p = 0.34 |
V9 3.7% | 0.5–10.5% | V10 5.4% | 0.1–8.7% | p = 0.35 |
V4.5 105.7 cc | 64.5–173.5 cc | V5 41.47 cc | 3.1–82.3 cc | p = 0.001* |
V4.5 25.0% | 15.1–38.5% | V5 9.6% | 0.8–18.3% | p = 0.002* |