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Table 4 Factors correlating with three year grade ≥ 2 GU toxicity free survival in univariate analysis

From: Acute and late toxicity in prostate cancer patients treated by dose escalated intensity modulated radiation therapy and organ tracking

Factor

Group

No. of Patients

% TFS

No. at Risk*

p†

All patients

 

39

69.2

5

 

Age (years)

≤ 69

20

85.0

4

 
 

> 69

19

52.6

1

.025

Hormonal therapy

no

10

40.0

0

 
 

yes

29

79.3

5

.016

PGUM (grade)

0–1

29

86.2

4

 
 

2–3

10

20.0

1

<.001

PTV (cm3)

≤ 105

20

80.0

2

 
 

> 105

19

57.9

3

.128

PTV Dmax (Gy)

≤ 84.3

21

76.2

3

 
 

> 84.3

18

61.1

2

.199

Bladder V47 (%)

≤ 28

20

75.0

3

 
 

> 28

19

63.2

2

.437

  1. Abbrevations: TFS = toxicity free survival; PGUM = pre-treatment genitourinary morbidity; PTV = planning target volume; PTV Dmax = maximum dose within the PTV; Bladder V47 = percentage of bladder wall receiving at least 47 Gy * Number at risk at three years; † Log-rank test