| |
Pre-Tx
|
Acute†
|
Late‡
|
Last late§
|
---|
Toxicity
|
Grade
|
n (%)
|
n (%)
|
n (%)
|
n (%)
|
---|
Diarrhea
|
0
|
39 (100)
|
29 (74)
|
36 (92)
|
38 (97)
|
|
1
|
0
|
9 (23)
|
3 (8)
|
1 (3)
|
|
2
|
0
|
1 (3)
|
0
|
0
|
Rectal pain
|
0
|
38 (97)
|
34 (87)
|
37 (96)
|
38 (97)
|
|
1
|
1 (3)
|
5 (13)
|
1 (3)
|
1 (3)
|
|
2
|
0
|
0
|
1 (3)
|
0
|
Rectal bleeding
|
0
|
36 (92)
|
36 (92)
|
33 (85)
|
34 (87)
|
|
1
|
3 (8)
|
3 (8)
|
4 (10)
|
5 (13)
|
|
2
|
0
|
0
|
2 (5)
|
0
|
Highest GI*
|
0
|
36 (92)
|
25 (64)
|
30 (77)
|
32 (82)
|
|
1
|
3 (8)
|
13 (33)
|
6 (15)
|
7 (18)
|
|
2
|
0
|
1 (3)
|
3 (8)
|
0
|
- Abbreviations: Pre-Tx = pre-treatment; * The highest toxicity in a patient was counted as a single event; † During therapy and until 3 months after completion; ‡ maximal late toxicity > 3 months after completion of therapy; § Incidence of late toxicity at last follow-up visit