Neuropsychological testing and biomarkers in the management of brain metastases

Radiation Oncology

Table 4 WBRT vs surgery plus WBRT in randomized trials

Study (ref)	Year	Treatment	(Gy)/number of fractions	n	Median survival (mo)	P Value
Patchell et al [22]	1990	Biopsy + WBRT	36 Gy/12	23	3.4	< 0.01
		S + WBRT		25	9.2
Vecht et al [23]	1993	WBRT	40Gy/10	31	6	0.04
		S + WBRT		32	10
Noordijk et al [24]	1994	WBRT	40Gy/10	34	6	0.04
		S + WBRT		32	10
Mintz et al [25]	1996	WBRT	30Gy/10	43	6.3	0.24
		S + WBRT		41	5.6

ISSN: 1748-717X