Radiation Oncology

Table 2 Mean values and the range of dosimetric data for the different treatment plans as planned and recalculated using

From: Developing and evaluating stereotactic lung RT trials: what we should know about the influence of inhomogeneity corrections on dose

	CC	UD				EPL
	Planned	Planned	p-value	Recalculated	p-value	Planned	p-value	recalculated	p-value
D₉₅ [Gy]	60.0	60.0	-	56.9 [42.1–63.4]	0.007	60.0	-	48.0 [34.6–56.1]	< 0.001
D₉₉ [Gy]	58.5 [57.6–59.5]	58.8 [57.8–59.8]	< 0.001	54.5 [39.6–62.0]	< 0.001	58.8 [58.1–59.7]	< 0.001	45.9 [32.6–53.7]	< 0.001
D_isoc [Gy]	74.3 [66.0–84.1]	66.6 [62.5–71.3]	< 0.001	72.7 [59.3–79.6]	0.19	67.1 [63.2–72.2]	< 0.001	61.7 [47.9–70.1]	< 0.001
D_mean [Gy]	66.9 [64.1–71.0]	64.1 [61.6–66.6]	< 0.001	65.0 [49.1–71.0]	0.11	64.3 [61.8–66.4]	< 0.001	55.2 [39.7–62.1]	< 0.001
D_max [Gy]	75.6 [67.8–87.4]	68.1 [63.0–73.3]	< 0.001	73.8 [61.3–81.7]	0.17	68.5 [63.8–76.5]	< 0.001	62.9 [48.0–74.2]	< 0.001
V_100%/V_PTV	1.13 [0.98–1.38]	1.09 [0.98–1.25]	0.14	0.98 [0.01–1.45]	0.08	1.09 [1.03–1.22]	0.026	0.27 [0.00–0.71]	< 0.001
V_50%/V_PTV	8.4 [4.5–18.2]	6.3 [4.4–12.6]	< 0.001	6.6 [4.9–12.2]	0.006	6.3 [4.1–12.0]	< 0.001	4.8 [3.1–6.5]	< 0.001
V_{20 Gy} [%]	6.6 [2.9–16.7]	5.6 [2.2–14.2]	< 0.001	6.0 [2.3–15.5]	0.017	5.2 [2.1–12.3]	< 0.001	4.1 [1.5–10.9]	< 0.001
V_{10 Gy} [%]	13.7 [7.3–35.8]	12.1 [5.9–29.9]	< 0.001	13.1 [6.1–33.5]	0.038	12.0 [5.5–29.5]	< 0.001	10.9 [4.6–27.3]	< 0.001
MLD [cGy]	456 [257–941]	396 [203–828]	< 0.001	439 [223–905]	0.18	394 [205–738]	< 0.001	355 [183–683]	< 0.001

full inhomogeneity corrections, and the p-values for the paired-sample t-test comparing the UD and EPL calculated and recalculated plans to the CC plan.

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