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Table 1 Clinical Characteristics of Group A (no intervention) and Group B (intervention)

From: A psychoeducational intervention reduces the need for anesthesia during radiotherapy for young childhood cancer patients

  Group A
No Intervention
Group B
Intervention
P
  N (%) N (%)  
Number of RT courses 154 63.1% 90 36.9%  
Number of RT fractions 2580 62.3% 1561 37.7%  
   Sex      
Male 103 66.9% 61 67.8%  
Female 51 33.1% 29 32.2%  
   Age      
Median 7.9   8.1   
Mean 9   8.9   
Range 0.0 – 19.0   1.6 – 19.1   
   Anesthesia      
Yes 33 21.4% 8 8.9% p = 0.015
No 121 78.6% 82 91.1%  
   Age of those with anesthesia (Years)      
Median 3.2   2.7   p < 0.001
Mean 3.2   2.7   
Range 0.0 – 12.0   1.6 – 4.3   
Standard Deviation 2.1   0.9   
   Total dose of irradiation (Gray)      
Median 24.0   20.0   
Mean 28.9   31.2   
Range * 4.0 – 59.4   6.0 – 68.0   
Standard Deviation 16.8   19.0   
   Total times of irradiation      
Median 12.5   12.0   
Mean 16.8   17.3   
Range 1.0 – 54.0   3.0 – 36.0   
Standard Deviation 10.3   10.6   
   Diagnostic group      
CNS tumor 31 20.1% 25 27.8%  
Leukemia/Lymphoma 67 43.5% 43 47.8%  
Solid tumor 56 36.4% 22 24.4%  
   Site of irradiation      
Cranial irradiation 98 63.6% 56 62.2%  
Extracranial irradiation 56 36.4% 34 37.8%  
   Positioning      
Prone position 19 12.3% 19 21.1%  
Supine position 129 83.8% 64 71.1%  
Other position 6 3.9% 7 7.8%  
   Intent of Radiotherapy      
Curative 132 85.7% 83 92.2%  
Palliative 22 14.3% 7 7.8%  
  1. Calculation of clinical characteristics is based on number of RT courses and not RT fractions.
  2. In 6 patients in group A and 4 patients in group B low total irradiation dosages of 4 to 6 Gray were applied for pain reduction for palliative treatment, and 4.5 and 6 Gray in a curative setting in two infants with neuroblastoma in Group B.