Comparing two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the hypofractionated treatment of high-risk prostate cancer

Table 7 Dose Volume Metrics for the Organs at Risk

	3DCRT	Targeting	Avoidance	ANOVA	3DCRT – Targeting	3DCRT – Avoidance	Targeting – Avoidance
Rectum
D15%	67.68 ± 2.60	59.81 ± 6.44	62.45 ± 4.46	P = 0.004	P = 0.033	NS	NS
D25%	63.57 ± 3.62	52.14 ± 5.16	55.27 ± 4.81	P < 0.001	P < 0.001	P < 0.001	NS
D35%	59.39 ± 3.97	46.97 ± 4.58	50.00 ± 4.08	P < 0.001	P < 0.001	P < 0.001	P = 0.04
D50%	54.08 ± 3.22	39.99 ± 5.25	43.76 ± 3.18	P < 0.001	P < 0.001	P < 0.001	P = 0.034
Bladder
D15%	69.14 ± 1.99	62.89 ± 4.61	63.75 ± 3.06	P = 0.004	P = 0.05	P = 0.02	NS
D25%	64.60 ± 5.37	56.01 ± 5.51	57.79 ± 4.43	P < 0.001	P < 0.001	P = 0.001	NS
D35%	60.54 ± 6.44	49.95 ± 6.51	52.61 ± 5.55	P < 0.001	P = 0.001	P = 0.001	P = 0.034
D50%	56.69 ± 5.34	42.40 ± 7.56	44.97 ± 4.83	P < 0.001	P < 0.001	P = 0.002	NS
Femora
LFHD15%	62.84 ± 3.70	40.23 ± 3.64	42.29 ± 1.07	P < 0.001	P = 0.004	P < 0.001	NS
RFHD15%	62.55 ± 3.33	43.08 ± 10.03	41.83 ± 1.34	P < 0.001	P < 0.001	P < 0.001	NS
Small Bowel
D5%	53.47 ± 1.63	42.50 ± 2.02	46.16 ± 2.48	P < 0.001	P < 0.001	P = 0.005	P = 0.002
D1%	54.31 ± 1.57	45.75 ± 2.46	50.00 ± 3.08	P < 0.001	P = 0.001	NS	P = 0.003

ISSN: 1748-717X