Figure 7

Dose contribution compensation. a) For the reference motion phase dose contributions from each grid position (x, y, E, N) on grid positions irradiated later (x', y', E', N') are calculated based on lateral distance r and depth z'. b) Changes in dose contribution ΔD are computed based on the 4DCT phase of interest including the adaptation of Bragg peak position Δ(x, y, z) and Δ(x', y', z'). This results in a shift of the depth dose distribution d(E, z + Δz), shift of z' (by Δz'), as well as a change in lateral distance (r').