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Figure 10 | Radiation Oncology

Figure 10

From: The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro

Figure 10

Increased pro-apoptotic efficacy of the combination involves enhanced damage of the mitochondria. T98G were irradiated with a single dose of 0, 2.5, 5 or 10 Gy and subsequently treated with 0, 12.5, 25 or 50 μM ErPC as indicated. Induction of apoptosis was quantified 48 h after treatment by FACS upon staining with TMRE. Data show (A) means ± s.d., n = 3 or (B) original histograms of one representative experiment.

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