Table 1 Results of dose-volume histogram analysis. Results of dose-volume histogram (DVH) analysis of cardiac structures (RV: right ventricle, RA: right atrium, LV: left ventricle, LA: left atrium, RCA: right coronary artery, LAD: left anterior descending artery, LCX: left circumflex artery). Median (min-max) doses are given for patients treated with mantle field alone (MF), mantle field + rotation boost (MF+ROT) and mantle field + dorsal boost (MF+DORS), both as relative doses (in %) and absolute doses (in Gy). Values significantly different from MF are indicated by bold print (*= p < 0.05). Significantly higher relative doses to RV, RA and RCA with MF alone are compensated by reduced total prescription doses for MF technique and by sparing of right heart structures with boost techniques, resulting in comparable absolute total doses between techniques. (# indicates DVH parameters in which a significant inverse correlation between 2-D heart area shielded by block and the respective DVH value was observed.)
structure | relative dose [%] | absolute dose [Gy] | ||||
|---|---|---|---|---|---|---|
(# = significant correlation 2D–3D) | MF n = 26 | MF+ROT n = 18 | MF+DORS n = 7 | MF n = 26 | MF+ROT n = 18 | MF+DORS n = 7 |
RV min # | 30 (16–98) | 24 (12–49) | 18 (14–87) | 11 (3–35) | 11 (5–22) | 8 (6–40) |
RV max | 129 (108–147) | 117 (98–141)* | 114 (94–124)* | 49 (23–58) | 48 (43–58) | 52 (39–52) |
RV median | 117(49–132) | 101(64–118)* | 94 (88–114) | 43 (18–53) | 43 (22–52) | 43 (36–48) |
RV mean # | 114 (61–127) | 99 (74–112) | 85 (80–104) | 41 (19–52) | 41 (25–47) | 37 (35–46) |
LV min | 18 (12–46) | 16 (9–27) | 15 (10–20) | 7 (2–16) | 8 (4–11) | 6 (5–9) |
LV max | 119 (32–147) | 107 (52–129) | 96 (92–122) | 46 (12–53) | 45 (18–55) | 44 (39–51) |
LV median # | 42 (17–99) | 41 (19–95) | 40 (22–55) | 16 (6–41) | 18 (7–39) | 17 (10–25) |
LV mean # | 56 (17–91) | 50 (26–83) | 47 (33–58) | 22 (6–35) | 23 (10–34) | 19 (15–25) |
LA min | 84 (28–97) | 79 (48–95) | 73 (40–89) | 30 (10–37) | 34 (16–40) | 32 (18–37) |
LA max | 102 (84–116) | 106 (86–124) | 93 (85–110) | 38 (18–46) | 45 (36–49)* | 43 (35–46) |
LA median | 92 (76–106) | 98 (79–108) | 80 (75–103) | 35 (16–41) | 41 (33–45)* | 36 (33–43) |
LA mean | 92 (76–106) | 97 (78–107) | 81 (75–103) | 35 (16–41) | 41 (33–45)* | 36 (33–43) |
RA min | 86 (20–103) | 75 (37–104) | 75 (43–101) | 31 (8–38) | 30 (17–44) | 33 (19–42) |
RA max | 123 (100–142) | 116 (99–143) | 107 (91–119)* | 47 (21–55) | 49 (42–57) | 49 (38–50) |
RA median | 105 (76–122) | 101 (88–125) | 90 (86–110) | 39 (19–48) | 43 (33–51) | 41 (35–46) |
RA mean | 105 (68–122) | 100 (84–122) | 89 (86–110) | 39 (19–47) | 42 (32–50) | 41 (35–46) |
RCA min | 101 (48–128) | 90 (58–108) | 84 (67–99) | 37 (19–51) | 38 (23–47) | 38 (31–42) |
RCA max | 127 (99–147) | 112 (93–144)* | 109 (94–122)* | 48 (22–56) | 46 (40–56) | 50 (39–51) |
RCA median | 120 (90–141) | 104 (89–125)* | 103 (92–120) | 45 (22–55) | 43 (37–55) | 47 (38–50) |
RCA mean | 116 (91–136) | 102 (86–121)* | 96 (90–11,6) | 44 (21–54) | 42 (36–53) | 44 (37–48) |
LAD min # | 23 (15–80) | 20 (11–34) | 18 (13–33) | 9 (3–28) | 10 (5–14) | 8 (6–15) |
LAD max # | 109 (25–139) | 104 (48–122) | 92 (68–120) | 39 (9–55) | 44 (16–50) | 40 (31–50) |
LAD median # | 60 (19–121) | 66 (28–113) | 39 (26–108) | 20 (7–48) | 30 (10–47) | 18 (12–45) |
LAD mean # | 61 (19–112) | 60 (30–96) | 53 (35–81) | 23 (7–46) | 28 (10–39) | 22 (16–34) |
LCX min # | 68 (22–93) | 66 (38–91) | 53 (28–79) | 25 (8–37) | 29 (13–38) | 22 (13–33) |
LCX max | 91 (44–111) | 96 (56–112) | 87 (81–108) | 34 (16–43) | 42 (19–46)* | 40 (33–45) |
LCX median # | 80 (22–95) | 79 (42–95) | 75 (40–95) | 29 (8–39) | 35 (14–40) | 31 (18–40) |
LCX mean # | 79 (26–96) | 81 (43–94) | 71 (46–92) | 29 (9–39) | 35 (15–40)* | 29 (21–39) |