Table 1 Patient characteristics
Total number of patients | 34 |
Sex | |
Male | 18 (52.9%) |
Female | 16 (47.1%) |
Age median in years (range) | |
Primary situation | 47 (20–71) |
Re-RT situation | 59 (39–75) |
Number of RTs in primary situation | 34 |
Number of RTs in recurrence situation (re-RT) | 12 |
Time between initial diagnosis and radiation in months (range) | |
Primary situation | 9 (1–105) |
Re-RT situation | 138.5 (85–243) |
Time between (re-)surgery and RT in months (range) | |
Primary situation | 4 (1–105) |
Re-RT situation | 7 (2–28) |
Tumor localization | |
Brain | 34 |
Extent of primary operation as declared by surgeon in primary situation | |
Resection | 26 (76.5%) |
Biopsy | 8 (23.5%) |
Residual tumor on planning MRI | |
Primary situation | |
Yes | 20 |
No | 14 |
Re-RT situation | |
Yes | 11 |
No | 1 |
Radiation technique in primary situation | |
3D-conformal RT | 12 (35.3%) |
IMRT/Tomo | 6 (17.6%) |
Stereotactic RT | 0 (0%) |
Proton RT | 15 (44.1%) |
C12-Ion RT | 1 (2.9%) |
Radiation technique for re-RT situation | |
3D-conformal RT | 1 (8.3%) |
IMRT/Tomo | 1 (8.3%) |
Stereotactic RT | 2 (16.6%) |
Proton RT | 0 |
C12-Ion RT | 8 (66.7%) |
Recurrence after first RT | |
No | 15 (44.1%) |
Yes | 14 (41.2%) |
Unknown | 5 (14.7%) |
Median follow-up in months | |
Primary situation | 60 (0–282) |
Re-RT situation | 26.5 (0 – 72) |
WHO grade | |
WHO 2 | 10 (29.4%) |
WHO 3 | 19 (55.9%) |
Unknown | 5 (14.7%) |
Median PTV in ml (range) | |
Primary situation | 128 (21–383) |
Re-RT situation | 125.5 (6–254) |
Median total RT Dose in Gy (range) | |
Primary situation | 60.0 (47.9–75.00) |
Re-RT situation | 63.8 (40.0–90.0) |
Dose per fraction in Gy (range) | |
Primary situation | 2.0 (1.8–3.0) |
Re-RT situation | 3.0 (2.0–18.0) |