| Before registration | Before treatment | During treatment | After treatment (months) |  > 1 year | |||
---|---|---|---|---|---|---|---|---|
3 | 6 | 9 | 12 | |||||
Patient background | O | Â | Â | Â | Â | Â | Â | Â |
General condition | O | O | Â | O | O | O | O | As needed |
Imaging examination | O | Â | Â | O | O | O | O | As needed |
Physiological test | O | Â | Â | Â | Â | Â | Â | As needed |
Blood test | O | Â | Â | O | O | O | O | As needed |
Quality of life | Â | O | Â | O | O | O | O | Â |
Toxicities ≥ grade 2 (CTCAE v5.0) |  |  | O | O | O | O | O | As needed |
Therapeutic efficacy evaluation | Â | Â | Â | O | O | O | O | As needed |