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Table 1 Implementation process for MR-only workflow for radiotherapy of CNS tumours

From: Contouring practices and artefact management within a synthetic CT-based radiotherapy workflow for the central nervous system

 

Phase 1

Phase 2

Objective

Commissioning

Validation

Simulation imaging

CT and MRI

CT and MRI

MR-CT image registration

Rigid registration based on bone anatomy

Rigid registration based on bone anatomy

Delineation

Bones, Body and Brain on CT. Target and OARs on MRI

Bones, Body and Brain on sCT. Target and OARs on MRI

Dose optimisation

Performed on CT

Performed on sCT

Patient position verification

CT-CBCT

sCT-CBCT

Patient cohort

112 CNS cancer patients

30 glioblastoma g.IV patients