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Table 1 Normal tissue dose contraints

From: FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach

Tissue

Volume

Volume Max (Gy)

Max point dose (Gy)

Potential Adverse Outcome (≥ Grade 3) per TG101

Spinal Cord

< 1.2 cc

7

14

Myelitis

Lung (Right and Left)

1500 cc

7

NA-Parallel tissue

Basic Lung Function

Lung (Right and Left)

1000 cc

7.4

NA-Parallel tissue

Pneumonitis

Lung (Right and Left)

37%

8

NA-Parallel tissue

Pneumonitis

Heart/pericardium

15 cc

16

22

Pericarditis

Esophagus

5 cc

11.9

15.4

Stenosis/fistula