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Table 1 Baseline characteristics by study arm

From: Toxicity of external beam accelerated partial-breast irradiation (APBI) in adjuvant therapy of early-stage breast cancer: prospective randomized study

  

APBI

N = 42

WBI

N = 42

p-value

Age (years)

Median (Range)

65 (52, 77)

64 (51, 81)

0.070

Phototype

I/II

19 (45%)

20 (48%)

0.827

 

III/IV

23 (55%)

22 (52%)

 

Laterality

left

18 (43%)

21 (50%)

0.512

 

right

24 (57%)

21 (50%)

 

Grade

G1

25 (60%)

24 (57%)

0.825

 

G2

17 (40%)

18 (43%)

 

Histology

DCIS

2 (4.8%)

2 (4.8%)

0.911

 

NST

34 (81%)

32 (76%)

 
 

Other

6 (14%)

8 (19%)

 

Tumor size (mm)

0–9

24 (57%)

18 (43%)

0.422

 

10–14

13 (31%)

17 (40%)

 
 

15–20

5 (12%)

7 (17%)

 

ER (%)

90

0 (0%)

3 (7.1%)

0.121

 

95

2 (4.8%)

4 (9.5%)

 
 

100

40 (95%)

35 (83%)

 

PR (%)

< 10

8 (19%)

9 (21%)

0.267

 

10–79

10 (24%)

16 (38%)

 
 

80–100

24 (57%)

17 (40%)

 

Ki67 (%)

< 15

21 (50%)

25 (60%)

0.583

 

15–20

13 (31%)

12 (29%)

 
 

> 20

8 (19%)

5 (12%)

 

Number of sentinel lymph nodes removed

1

25 (60%)

22 (55%)

0.462

2

8 (19%)

12 (30%)

 
 

> 2

9 (21%)

6 (15%)

 
 

Omitted

0

2

 

Negative resection margin (mm)

Median (Range)

5 (2, 10)

5.5 (2, 15)

0.718

Cavity size (mm)

Median (Range)

30 (16, 69)

31 (13, 65)

0.629

 

< 30

22 (52%)

21 (50%)

0.827

 

≥ 30

20 (48%)

21 (50%)

 

Endocrine therapy during RT

None

9 (21%)

4 (9.5%)

0.345

 

AI

4 (9.5%)

5 (12%)

 
 

Tamoxifen

29 (69%)

33 (79%)

 
  1. Abbreviations: APBI = accelerated partial breast irradiation, WBI = whole breast irradiation, NST = non-specified tumor histology, ER = estrogen receptor, PR = progesterone receptor, RT = radiotherapy, AI = aromatase inhibitor, DCIS = Ductal Carcinoma In Situ