Table 1 Characteristics of patients included in this study protocols

Total patients

54

50

49

30

57

-

Sex (M/F No.)

(%)

38/16

70/30

32/18

64/36

40/9

82/18

24/6

80/20

48/9

84/16

0.089

Average Age (year)

62.1 ± 8.5

63.2 ± 11.6

62.2 ± 9.9

67.9 ± 9.9

56.7 ± 8.7

< 0.001

No. of patients

>=60 years

< 60

34

20

33

17

30

19

24

6

20

37

T stage (No.)

T1

T2

T3

T4

T4a

T4b

Tx

8

22

15

5

0

0

4

4

20

17

1

6

2

0

9

13

20

5

0

0

2

1

14

5

6

1

2

1

11

19

16

4

0

0

0

0.046

N stage

N0

N1

N2

N2a

N2b

N2c

N3

N3a

N3b

3

7

38

0

0

0

6

0

0

18

4

25

0

0

0

3

0

0

10

10

0

6

15

7

1

0

0

5

4

0

0

10

9

1

0

1

10

9

2

2

24

8

2

0

0

< 0.001

TNM stage

I

II

III

IV

V

VI

IVA

IVB

IIB

IV1A

0

1

52

0

0

0

0

0

0

1

2

7

9

0

0

0

27

5

0

0

1

2

19

0

0

0

25

1

1

0

0

2

5

0

0

0

17

5

1

0

2

2

13

0

0

0

38

2

0

0

< 0.001

Primary site

Unknown

Oropharynx

Nasopharynx

Larynx

Hypopharynx

4

47

2

0

1

0

36

3

10

1

2

34

5

6

2

0

14

4

7

5

2

47

2

4

2

< 0.001

Therapy

Radiation only

CHRT

Surgery + RT

Surgery + CHRT

3

51

0

0

15

35

0

0

3

46

0

0

5

25

0

0

9

26

5

17

< 0.001

RT modality

IMRT/TOMO

IMRT

VMAT

IMRT

IMRT

Total prescribed dose (Gy, (median ± SD)

70 ± 1.6

69 ± 21

71 ± 2

68 ± 3.1

70 ± 2.3

Outcome

VS(alive/dead)

50/4

41/9

44/5

16/14

40/17

< 0.001

Time (days)*

Average

Min

Max

1190

350

1806

1189

245

2001

1277

361

2119

1195

194

2136

2235

193

3542