Table 1 Schedule for Screening and follow-up of the ALA-RDT in GBM study
Screening for cohorts 0 and 1 | Screening for cohorts 2 to 8 | Follow-Up 1 (all patients) | Follow-Up 2 (all patients) | |
|---|---|---|---|---|
Day | -7 to -4 before surgery | -14 to -2 before first RDT | 12 weeks after firstadjuvant RT | 6 months after firstadjuvant RT |
Informed consent: | X | X | ||
In- / Exclusion criteria: | X | X | ||
MRI: | MRI outside screening period used for diagnosis and as baseline value | MRI up to 72 h after surgery, performed outside study protocol Screening period used for diagnosis and baseline | X | X |
Medical and neurological examination | X | X | X | X |
Laboratory panel | X | X | X | X |
Medical / surgical history | X | X |