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Fig. 2 | Radiation Oncology

Fig. 2

From: The radiation- and chemo-sensitizing capacity of diclofenac can be predicted by a decreased lactate metabolism and stress response

Fig. 2

LDH activity and expression levels in LS174T, LoVo, A549 and MDA-MB-231 cancer cells after diclofenac treatment. LDH activity assay of LS174T (A), LoVo (C), A549 (E) and MDA-MB-231 (G) cancer cells treated with diclofenac (0, 0.1 and 0.2 mM) for 48 h. Representative immunoblot showing the expression of LDHA and LDHB 48 h after diclofenac treatment in LS174T (B), LoVo (D), A549 (F) and MDA-MB231 (H) cancer cells. Quantification of the LDHA and LDHB signals of at least 3 independent experiments are shown in the bar charts above. The one way ANOVA test was used to evaluate significant differences (*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001)

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