Fig. 1From: Evaluation of PTV margins with daily iterative online adaptive radiotherapy for postoperative treatment of endometrial and cervical cancer: a prospective single-arm phase 2 studyWorkflow of this study to determine the optical PTV margins and explore the clinical and dosimetric advantages of reduced margins. The minimum adaptive margin expansion for the training cohort was determined by registering pre- and posttreatment iCBCT images with respect to bony anatomy. A separate cohort with a total of 125 fractions of iCBCT scans was uploaded to the oART simulator for dosimetric advantage evaluation with the minimum adaptive margins. The minimum adaptive expansion was verified in a validation cohort, and acute toxicity was studiedBack to article page