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Table 5 Details concerning applied RT dose and fractionating scheme for all patients of the study (N = 77) with corresponding EQD2 (α/β:10) and BED10

From: Hemostatic radiotherapy in clinically significant tumor-related bleeding: excellent palliative results in a retrospective analysis of 77 patients

Applied Dose (Gy)

1st Fractionation (Fractions*Gy)

2nd Fractionation (Fractions*Gy)

3rd Fractionation (Fractions*Gy)

EQD2 (α/β:10)

BED10

Patients: N (%)

Primary Tumor

Bleeding stop achieved (%)

Comments

9

3 × 3

  

9.75

11.7

4 (5.6)

H&N, pelvic A-CUP, CC, LC

50

2/4 RT aborted due to death of patient

10

1 × 10

  

16.67

20

1 (1.3)

OC

100

Brachytherapy

10

2 × 5

  

12.5

15

1 (1.3)

BC

100

RT aborted prematurely after achieving bleeding stop due to general deterioration

12

4 × 3

  

13

15.6

2 (2.6)

CC, EC

100

 

12

6 × 2

  

12

14.4

1 (1.3)

CC

100

RT aborted prematurely after achieving bleeding stop due to patients’ decision

13

3 × 3

2 × 2

 

13.75

16.5

1 (1.3)

pelvic A-CUP

0

RT aborted prematurely due to patients’ decision before achieving bleeding stop

18

3 × 3

5 × 1.8

 

18.6

22.32

1 (1.3)

PC

100

RT aborted prematurely due to general deterioration

19

3 × 3

5 × 2

 

19.75

23.7

1 (1.3)

EDC

0

1/14 RT aborted prematurely without achieving bleeding stop due to patients ‘ decision

20

5 × 4

  

23.33

28

1 (1.3)

RCC

100

 

20

4 × 5

  

25

30

1 (1.3)

RC

100

 

40

5 × 8

  

60

72

1 (1.3)

UC

100

 

30

6 × 5

  

37.5

45

1 (1.3)

H&N

100

Brachytherapy

24

1 × 3

1 × 5

1 × 4

27.17

32.6

1 (1.3)

EDC

100

4th Fractionation: 4 × 3 Gy

24

4 × 2

4 × 4

 

26.67

32

1 (1.3)

LC

0

RT aborted prematurely

28.8

3 × 3

11 × 1.8

 

29.22

35.06

1 (1.3)

CC

100

RT aborted prematurely due to general deterioration

30

15 × 2

  

30

36

3 (3.9)

MM: 2, CC

100

1/3 low dose due to Reirraditation

30

10 × 3

  

32.5

39

4 (5.2)

CC, BC, EC, PC

50

4/4 RT aborted prematurely, 2/4 due to complications, 1/4 due to death by pulmonary artery embolism, 1/4 after achieving bleeding stop due to patients’ decision

30.6

3 × 3

2 × 1.8

9 × 2

31.29

37.55

1 (1.3)

CC

100

 

30.6

3 × 3

12 × 1.8

 

30.99

37.19

1 (1.3)

BLC

100

 

33

11 × 3

  

35.75

42.9

1 (1.3)

LC

0

RT aborted due to death of patient

36

13 × 2

  

36

43.2

1 (1.3)

BLC

0

RT aborted due to death of patient

36

12 × 3

  

39

46.8

2 (2.6)

EDT

100

1/2 RT aborted prematurely after achieving bleeding stop due to patients’ decision

39

13 × 3

  

42.25

50.7

14 (18.2)

EDT: 3, LC: 3, UC: 3, BLC: 2, PC, H&N, RC

85.7

 

40

20 × 2

  

40

48

4 (5.2)

GC, CC; BLC, PC

100

 

45

15 × 3

  

48.75

58.5

2 (2.6)

BLC

100

 

45

3 × 3

18 × 2

 

46.45

54.9

3 (3.9)

CC, EDT, US, UC

100

 

45

1 × 3

21 × 2

 

45.25

54.3

1 (1.3)

EDT

100

 

45

3 × 3

20 × 1.8

 

45.15

54.18

2 (2.6)

CC, OC

100

 

45

25 × 1.8

  

44.25

53.1

4 (5.2)

CC, RC, AC, PaC

100

 

49

3 × 3

20 × 2

 

49.75

59.7

2 (2.6)

CC, BLC

100

 

50

25 × 2

  

50

60

1 (1.3)

LS, RC

100

 

50.4

28 × 1.8

  

49.56

59.47

1 (1.3)

BLC

100

Change to curative concept after achieving bleeding stop

54

3 × 3

25 × 1.8

 

54

64.8

1 (1.3)

RC

100

Change to curative concept after achieving bleeding stop

59

3 × 3

25 × 2

 

59.75

71.7

1 (1.3)

LC

100

Change to curative concept after achieving bleeding stop

59.4

33 × 1.8

  

58.41

70.09

1 (1.3)

CC

100

 

59.4

3 × 3

28 × 1.8

 

59.31

71.17

7 (9)

CC

100

5/7 Change to curative concept after achieving bleeding stop, additional Brachytherapy

65

5 × 3

25 × 2

 

66.25

79.5

1 (1.3)

LC

100

Change to curative concept after achieving bleeding stop

  1. CC carcinoma of the cervix, BC breast carcinoma, BLC bladder cancer, EC esophageal carcinoma, EDC endometrioid carcinoma, OC ovarial carcinoma, LC lung cancer, A-CUP Adeno-Cancer of unknown primary, H&N cancer of the head and neck, RC rectum carcinoma, PC prostate carcinoma, RCC renal cell carninoma, AC anal carcinoma, GC gastric carcinoma, LS liposarcoma, PaC pancreatic carcinoma, MM malignant melanoma, UC urothel carcinoma other than bladder, US uterine sarcoma
  2. If not stated otherwise in the comment section, percutaneous RT was applied