Fig. 3
From: Prospects for online adaptive radiation therapy (ART) for head and neck cancer
a Dependence of the ranks of the EUDCTV by the scheduled plan (EUDsCTV) (1 for the highest EUDsCTV, 0 for the lowest EUDsCTV; for the 44 adaptive fractions with non-missing values) on the deviation of the tongue back in cranial (+) or caudal (−) direction between CBCT1 and the planning CT, p = 0.0002 [in (mm) Spearman correlation coefficient rs =  − 0.52 (95% CI − 0.71 to − 0.26)]. b Dependence of the ranks of the EUDCTV by the scheduled plan (EUDsCTV) (1 for the highest EUDsCTV, 0 for the lowest EUDsCTV; for the 44 adaptive fractions with non-missing values) on the maximum craniocaudal deviation of the os hyoideum in cranial (+) or caudal (−) direction between CBCT1 and the planning CT, p = 0060 [in (mm) Spearman correlation coefficient rs =  − 0.40 (95% CI − 0.63 to − 0.12)]. c Dependence of the ranks of the EUDCTV by the scheduled plan (EUDsCTV) (1 for the highest EUDsCTV, 0 for the lowest EUDsCTV; for the 44 adaptive fractions with non-missing values) on the maximum overall deviation of the os hyoideum in cranial (+) or caudal (−) as well as in posterior (+) or anterior (−) direction between CBCT1 and the planning CT, p = 0.0077 [in (mm) Spearman correlation coefficient r =  − 0.39 (95% CI − 0.62 to − 0.11)]. Highlights that the EUDCTV by the scheduled plan (EUDsCTV) strongly depends on the deviation of the tongue back and os hyoideum. EUD: Equivalent Uniform Dose, s: scheduled plans and corresponding EUDs