Fig. 1
From: Prospects for online adaptive radiation therapy (ART) for head and neck cancer
a Empirical distribution functions of the EUDCTV values per dose fraction by the adaptive and scheduled plans. b Adaptation plot of EUDaCTV (EUD within the CTV in the adaptive plan). EUDaCTV remained at about 100% of the planned EUD for the DIR-based accumulated dose distributions independent from the EUDsCTV, implying that predominantly patients with poor EUD in the scheduled plan benefited from adaptation (p = 0.11). The intercept was 99.5% ± 3.5%, the slope was 0.024% ± 0.035% (p = 0.5). c Empirical distribution functions of the dose homogeneity by the adaptive and scheduled plans. Dose homogeneity of the dose distributions within the CTV was significantly better for the adaptive plans. The empirical distribution functions of the differences Dmax_CTV − D99_CTV as a measure of dose homogeneity with smaller differences found for the adaptive in comparison to the scheduled plans (p < 0.0001, signed rank test for paired differences between homogeneity measures from the same fraction)