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Table 2 RID lesion location

From: Histopathologically confirmed radiation-induced damage of the brain – an in-depth analysis of radiation parameters and spatio-temporal occurrence

 

All lesions

High-grade glioma

Brain metastasis

Hemisphere

   

 Left

19 (55.9%)

10 (55.6%)

9 (56.3%)

 Right

14 (41.2%)

8 (44.4%)

6 (37.5%)

 Bihemispheric

1 (2.9%)

0 (0.0%)

1 (6.3%)

Lobe

Involvement*

   

 Frontal

19 (55.9%)

13 (72.2%)

6 (37.5%)

 Temporal

12 (35.3%)

8 (44.4%)

4 (25.0%)

 Parietal

9 (26.5%)

2 (11.1%)

7 (43.8%)

 Occipital

2 (5.9%)

0 (0.0%)

2 (12.5%)

 Cerebellar

1 (2.9%)

0 (0.0%)

1 (6.3%)

Subventricular zone

involvement

18 (52.9%)

14 (77.8%)

4 (25.0%)

Basal ganglia involvement

10 (29.4%)

9 (50.0%)

1 (6.3%)

White matter involvement

34 (100.0%)

18 (100.0%)

16 (100.0%)

Cortex involvement

32 (94.1%)

17 (94.4%)

15 (93.8%)

  1. RID, radiation-induced damage
  2. *only involvement of ≥5% was considered, in order to account for minor registration uncertainties
  3. lesion within a 5 mm margin along the lateral wall of the lateral ventricles