Fig. 1

Kaplan-Meier curves showing the differences of the overall survival after GKRS1 between different treatment groups. A There is no difference in the median overall survival between female (8.8 months, 95% CI = 3.9-13.7) and male patients (5.7 months, 95% CI = 2.8-8.5; p=0.397). B Even though a trend towards a longer median overall survival in patients with a KPS ?80% (7.4 months, 95% CI = 6.3-8.4) compared to those with a KPS <80% (5.2 months, 95% CI = 2.2-8.3) could be observed, the results were statistically not significant (p=0.069). C Patients with a single BM (7.9 months, 95% CI = 3.3-12.5) at GKRS1 had a statistically significant longer median overall survival after GKRS1 compared to patients with multiple BM (4.4 months, 95% CI = 1.8-7.1, p=0.037). D A trend towards a longer median overall survival in patients with RPA class II (7.2 months, 95% CI = 5.4-9.1) compared to patients with RPA class III (2.2 months, 95% CI = 0-6.6) could be observed, however, the results were statistically not significant (p=0.087). BM brain metastasis, CI Confidence Interval, GKRS Gamma Knife Radiosurgery, KPS Karnofsky performance status scale, RPA Recursive partitioning analysis