Target volumes/ Organs at risk | Dose parameters | First submission (n = 26) | Final submission (n = 26) | P value‡ | ||||
---|---|---|---|---|---|---|---|---|
Optimal No. (%) | Acceptable No. (%) | Optimal plus acceptable No. (%) | Optimal No. (%) | Acceptable No. (%) | Optimal plus acceptable No. (%) | |||
PTVcw | V100% | 7 (26.9) | 11 (42.3) | 18 (69.2) | 11 (42.3) | 14 (53.8) | 25 (96.2) | 0.016 |
Dmax/V120% | 20 (76.9) | 4 (15.4) | 24 (92.3) | 15 (57.7) | 10 (38.5) | 25 (96.2) | 1.000 | |
V110% | 23 (88.5) | 2 (7.7) | 25 (96.2) | 23 (88.5) | 3 (11.5) | 26 (100.0) | 1.000 | |
PTVsc + ax | V100% | 15 (57.7) | 5 (19.2) | 19 (76.9) | 13 (50.0) | 13 (50.0) | 26 (100.0) | 0.031 |
Dmax/V120% | 23 (88.5) | 3 (11.5) | 26 (100.0) | 24 (92.3) | 2 (7.7) | 26 (100.0) | NA | |
V110% | 23 (88.5) | 2 (7.7) | 25 (96.2) | 22 (84.6) | 3 (11.5) | 25 (96.2) | 1.000 | |
PTVim | V100% | 9 (34.6) | 5 (19.2) | 14 (53.8) | 8 (30.8) | 15 (57.7) | 23 (88.5) | 0.012 |
Dmax/V120% | 24 (92.3) | 2 (7.7) | 26 (100.0) | 25 (96.2) | 1 (3.8) | 26 (100.0) | NA | |
V110% | 24 (92.3) | 0 | 24 (92.3) | 24 (92.3) | 1 (3.8) | 25 (96.2) | 1.000 | |
Heart | Dmean | 4 (15.4) | 15 (57.7) | 19 (73.1) | 2 (7.7) | 24 (92.3) | 26 (100.0) | 0.016 |
V5Gy | 17 (65.4) | 3 (11.5) | 20 (76.9) | 22 (84.6) | 3 (11.5) | 25 (96.2) | 0.125 | |
LADCA | V40Gy | 3 (11.5) | 7 (26.9) | 10 (38.5) | 7 (26.9) | 10 (38.5) | 17 (65.4) | 0.039 |
Ipsilateral lung | Dmean | 11 (42.3) | 8 (30.8) | 19 (73.1) | 14 (53.8) | 8 (30.8) | 22 (84.6) | 0.250 |
V20Gy | 12 (46.2) | 13 (50.0) | 25 (96.2) | 17 (65.4) | 9 (34.6) | 26 (100.0) | 1.000 | |
V5Gy | 9 (34.6) | 8 (30.8) | 17 (65.4) | 11 (42.3) | 13 (50.0) | 24 (92.3) | 0.016 | |
Contralateral lung | V5Gy | 20 (76.9) | 4 (15.4) | 24 (92.3) | 21 (80.8) | 4 (15.4) | 25 (96.2) | 1.000 |
Contralateral breast | Dmean | 20 (76.9) | 6 (23.1) | 26 (100.0) | 23 (88.5) | 3 (11.5) | 26 (100.0) | NA |
Spinal Cord PRV | Dmax | 22 (84.6) | 3 (11.5) | 25 (96.2) | 26 (100.0) | 0 | 26 (100.0) | 1.000 |
Esophagus | Dmax | 21 (80.8) | 5 (19.2) | 26 (100.0) | 23 (88.5) | 3 (11.5) | 26 (100.0) | NA |
Ipsilateral Brachial plexus | Dmax | 13 (50.0) | 11 (42.3) | 24 (92.3) | 9 (34.6) | 15 (57.7) | 24 (92.3) | 1.000 |
Ipsilateral shoulder joint | V30 | 12 (46.2) | 4 (15.4) | 16 (61.5) | 16 (61.5) | 5 (19.2) | 21 (80.8) | 0.125 |
Thyroid gland | Dmean | 15 (57.7) | 9 (34.6) | 24 (92.3) | 16 (61.5) | 9 (34.6) | 25 (96.2) | 1.000 |
Liver | V5 | 21 (80.8) | 2 (7.7) | 23 (88.5) | 26 (100.0) | 0 | 26 (100.0) | NA |
Stomach | V5 | 10 (38.5) | 4 (15.4) | 14 (53.8) | 18 (69.2) | 6 (23.1) | 24 (92.3) | 0.002 |