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Table 2 Distribution of toxicities for different grades in the two different study arms. *p value is referred to Mann-Whitney U test

From: THeragnostic utilities for neoplastic DisEases of the rectum by MRI guided radiotherapy (THUNDER 2) phase II trial: interim safety analysis

32 Patients

Toxicity (CTCAE v 5.0)

N (%)

 
 

G1

22 (68.8)

G2

7 (21.9)

G3

1 (3.2)

Total

30 (93.8)

*p value

16 boost

11 (34.4)

4 (12.5)

0

15 (46.9)

0.54

16 no boost

11 (34.4)

3 (9.4)

1 (3.2)

16 (50)

 

Proctitis

7 (21.9)

1 (3.2)

1 (3.2)

9 (28.1)

 

Diarrhoea

12 (37.5)

2 (6.3)

1 (3.2)

15 (46.9)

 

Tenesmus

13 (40.7)

1 (3.2)

 

14 (43.9)

 

Mucorrhoea

15 (46.9)

3 (9.4)

 

18 (56.3)

 

Cystitis

8 (25)

 

1 (3.2)

9 (28.1)

 

Fatigue

7 (21.9)

1 (3.2)

 

8 (25)