Table 3 Comparisons of dosimetry data in NPC patients receiving PBT versus VMAT and with versus without TLN
| Â | Radiation dose to right temporal lobe | Radiation dose to left temporal lobe | Staging distribution | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dmax | D0.5Â cc | D1cc | D2cc | V50Gy (c.c.) | V20Gy (c.c.) | Dmax | D0.5Â cc | D1cc | D2cc | V50Gy (c.c.) | V20Gy (c.c.) | T4 (%) | T3/T4 (%) | |
VMAT versus PBT | ||||||||||||||
VMAT | 7297 (5994, 7460) | 6678 (5619,7198) | 6307 (5454,7009) | 5906 (4836,6477) | 4.38 (1.67,8.09) | 26.41 (15.55,41.36) | 7342 (5963,7493) | 6445 (5615,7321) | 6196 (5397,7248) | 5855 (4832,7135) | 4.64 (1.80,8.93) | 24.00 (14.65,40.36) | 34.90% | 60.60% |
PBT | 6880 (6467,7414) | 6057 (5472,6867) | 5675 (5108,6627) | 5076 (4485,6211) | 2.15 (1.23,5.68) | 11.89 (9.63,19.86) | 6979 (6027,7379) | 5980 (5340,6845) | 5650 (4952,6548) | 5001 (4303,6169) | 2.03 (0.81,4.98) | 12.55 (8.27,18.12) | 23.30% | 50.00% |
p value | 0.71 | 0.32 | 0.15 | 0.05 | 0.02 | < 0.01 | 0.82 | 0.10 | 0.03 | < 0.01 | < 0.01 | < 0.01 | 0.08 | 0.14 |
With TLN versus without TLN | ||||||||||||||
With TLN | 7453 (7137,7489) | 7070 (6345,7359) | 6873 (6078,7305) | 6489 (5854,7208) | 7.00 (5.00,9.00) | 43.00 (18.54,53.00) | 7583 (6713,7722) | 7300 (6426,7448) | 7018 (6250,7409) | 6651 (5849,7357) | 8.00 (4.00,16.00) | 40.00 (20.00,51.00) | 45.50% | 63.60% |
W/O TLN | 7096 (6283,7444) | 6211 (5497,7082) | 5870 (5221,6807) | 5491 (4590,6320) | 3.01 (1.39,6.62) | 17.97 (10.56,27.65) | 7115 (5983,7443) | 6192 (5412,7148) | 5806 (5100,6972) | 5346 (4413,6486) | 2.71 (1.14,6.54) | 15.77 (10.31.26.56) | 28.80% | 55.40% |
p value | 0.03 | 0.01 | < 0.01 | < 0.01 | < 0.01 | 0.03 | 0.01 | < 0.01 | < 0.01 | < 0.01 | < 0.01 | < 0.01 | 0.31 | 0.6 |