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Table 1 Patient and treatment characteristics

From: Definitive irradiation as a first treatment strategy for primary and metastatic sites of newly diagnosed IVB cervical cancer that presented with synchronous oligometastases

Patient and treatment characteristics (n = 60)

Midian age (years)

53 (29–84)

≥ 50 years

40 (67%)

<50 years

20 (33%)

Histology

 

Squamous cell

56 (93%)

Adenocarcinoma

4 (7%)

Pre-treatment MRI-based maximal diameter (mm)

43 (10–82)

>40 mm

35 (58%)

≤40 mm

25 (42%)

Pre-treatment SCC lever (ng/ml)

17.7 (0.4–70)

Chemotherapy

 

Yes

50 (83%)

Cycles

4 (1–6)

Regimen

Cisplatin

Nedaplatin

Platin-based doublet therapy

No

10 (17%)

Initial treatment

 

Neoadjuvant chemotherapy + CCRT/RT

31 (52%)

CCRT

14 (23%)

Radiotherapy alone

10 (17%)

CCRT/RT + adjuvant chemotherapy

5 (8%)

RT dose (Gy)

 

EBRT to pelvis with or without abdomen

45 (45–50)

Brachytherapy to primary lesion (EQD2)

40 (32–70)

EBRT boost to gross node disease

10 (8–14)

EBRT to distant LN

60 (60–74)

EBRT to metastatic organ

60 (60–70)

Metastatic Sites at Diagnosis

 

Supraclavicular lymph node

45

Inguinal lymph node

16

Axillary lymph node

4

Mediastinal lymph node

1

Lung Parenchymal metastases

3

Bony metastases in pelvis

3

Extrapelvic bony metastases

4

Other (adrenal gland, gluteus maximus)

2

Number of Metastatic sites at Diagnosis

 

1

43 (72%)

2

14 (23%)

3

2 (3%)

4

1(2%)