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Table 2 Univariate and multivariate analysis of relationship between treatment strategies and INN occurrence

From: Irradiation-induced nasopharyngeal necrosis (INN) in newly diagnosed nasopharyngeal carcinoma treated by intensity-modulated radiation therapy: clinical characteristics and the influence of treatment strategies

Variables

Univariate

Multivariate

OR (95% IC)

p value

OR (95% IC)

p value

No chemotherapy

1.092 (0.568–2.099)

0.792

3.035 (0.398–23.162)

0.284

AC

2.082 (0.602–7.194)

0.247

2.099 (0.530–8.315)

0.291

NC

0.632 (0.233–1.716)

0.368

0.554 (0.171–1.790)

0.324

CC

0.940 (0.501–1.763)

0.847

0.387 (0.057–2.605)

0.329

Target therapy

0.647 (0.320–1.312)

0.227

0.536 (0.252–1.141)

0.106

Local boost

7.360 (2.301–23.547)

0.001

7.768 (2.340–25.785)

0.001

Chemotherapy strategies (NC + CCRT, CCRT + AC, CCRT)

–

0.475

–

–

  1. AC adjuvant chemotherapy, NC neoadjuvant chemotherapy, CC Concurrent chemotherapy, RT radiotherapy