Organs | Parameters | Cumulative EQD2 (Gy, median, range) | Univariate analysis with grade ≥ 2 toxicity | ||
---|---|---|---|---|---|
OR | 95% CI | P value | |||
Lung (unilateral) | Mean dose | 20.19 (5.16–38.88) | 0.859† | 0.724–1.019 | 0.081 |
V20 (%) | 26.79% (5.75–68.25%) | 0.918† | 0.824–1.021 | 0.116 | |
Lung (bilateral) | Mean dose | 11.88 (2.50–20.73) | 0.824† | 0.638–1.064 | 0.138 |
V20 (%) | 11.67% (2.59–32.52%) | 0.894† | 0.762–1.049 | 0.171 | |
Proximal bronchial tree | D0.5 cc | 53.86 (0.39–124.57) | 0.980† | 0.948–1.014 | 0.244 |
D1cc | 46.88 (0.35–84.57) | 0.969† | 0.931–1.009 | 0.128 | |
D5cc | 17.87 (0.28–79.20) | 0.950† | 0.892–1.011 | 0.109 | |
D10cc | 11.55 (0.24–73.74) | 0.931† | 0.831–1.043 | 0.219 | |
D15cc | 8.56 (0.19–69.84) | 0.924† | 0.797–1.072 | 0.297 | |
D30cc | 1.26 (0.11–64.57) | 0.468† | 0.098–2.228 | 0.340 | |
Chest wall | D0.5 cc | 199.45 (142.05–357.78) | 1.024‡ | 0.998–1.051 | 0.066 |
D1cc | 179.44 (119.39–335.21) | 1.024‡ | 0.997–1.050 | 0.077 | |
D5cc | 131.28 (42.74–261.98) | 1.021‡ | 0.995–1.047 | 0.114 | |
D10cc | 110.07 (17.33–220.61) | 1.024‡ | 0.995–1.055 | 0.110 | |
D15cc | 97.22 (13.41–198.90) | 1.028‡ | 0.994–1.063 | 0.103 | |
D30cc | 75.64 (9.16–162.43) | 1.033‡ | 0.994–1.074 | 0.096 | |
Aorta | D0.5 cc | 32.63 (6.96–233.03) | – | – | – |
D1cc | 30.40 (6.45–195.23) | – | – | – | |
D5cc | 24.30 (5.19–99.37) | – | – | – | |
D10cc | 20.69 (4.69–69.04) | – | – | – | |
D15cc | 18.10 (4.18–66.20) | – | – | – | |
D30cc | 12.30 (1.54–59.15) | – | – | – | |
Esophagus | D0.5 cc | 18.25 (6.20–63.97) | – | – | – |
D1cc | 17.09 (5.70–61.28) | – | – | – | |
D5cc | 12.22 (1.56–50.37) | – | – | – | |
D10cc | 2.85 (0.32–27.04) | – | – | – | |
D15cc | 0.89 (0.21–18.61) | – | – | – | |
Heart | D0.5 cc | 32.80 (0.20–93.95) | – | – | – |
D1cc | 30.71 (0.20–90.38) | – | – | – | |
D5cc | 23.27 (0.19–79.56) | – | – | – | |
D10cc | 19.14 (0.17–71.93) | – | – | – | |
D15cc | 16.69 (0.16–70.19) | – | – | – | |
D30cc | 12.58 (0.15–67.12) | – | – | – |