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Table 3 Possible determinants affecting increment of CAC percentiles in breast cancer patients

From: Accelerated coronary calcium burden in breast cancer patients after radiotherapy: a comparison with age and race matched healthy women

Variables

β (95% CI)

p value

Laterality of disease

 Right-side BC

Ref

Ref

 Left-side BC

15.13 (2.37, 27.87)

0.020

Pathology stage

 I

Ref

Ref

 II

 − 10.46 (− 30.09–9.17)

0.296

 III

 − 5.71 (− 23.90–12.49)

0.539

 IV

 − 17.07 (− 51.09–17.46)

0.333

Pathology stage

 0 vs. I vs. II

Ref

Ref

 III vs. IV

0.215 (− 12.90, 13.33)

0.974

Surgery

 Mastectomy

Ref

Ref

 BCS

 − 3.08 (− 16.85, 10.70)

0.659

Chemotherapy

 No

Ref

Ref

 Yes

 − 6.94 (− 23.86, 9.98)

0.417

Hormone therapy

 No

Ref

Ref

 Yes

 − 2.10 (− 17.29, 13.10)

0.785

Targeted therapy

 No

Ref

Ref

 Yes

 − 6.10 (− 35.19, 22.10)

0.678

Overweight

 BMI < 24

Ref

Ref

BMI ≧ 24

 − 6.19 (− 19.21, 6.83)

0.347

Obese

 BMI < 27

Ref

Ref

BMI ≧ 27

1.18 (− 13.61, 15.97)

0.874

Diabetes

 No

Ref

Ref

 Yes

13.99 (− 3.62, 31.60)

0.118

Hypertension

 No

Ref

Ref

 Yes

1.62 (− 14.34, 17.59)

0.841

Hyperlipidemia

 No

Ref

Ref

 Yes

 − 1.59 (− 20.52, 17.34)

0.867

Total irradiation dose (Gy)

 − 0.37 (− 1.32, 0.58)

0.439

  1. CAC coronary artery calcium, BC breast cancer, BCS breast-conserving surgery, BMI body mass index, Gy gray
  2. Significant p value was in bold