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Table 1 Characteristics of the 90-patient cohort

From: Sparing of normal tissues with volumetric arc radiation therapy for glioblastoma: single institution clinical experience

Characteristic

Number of patients/Median value (Range)

P*

IMRT

VMAT

Diagnosis

0.49

 Glioblastoma

44

43

 

 Oligodendroglioma

1

0

 Astrocytoma

0

2

Tumor Location

0.32

 Frontal

14

23

 

 Occipital

2

1

 Parietal

8

6

 Temporal

13

6

 Thalamus

1

1

 2 or more lobes

7

8

Tumor Side

0.34

 Bilateral

4

5

 

 Left

24

17

 Right

17

23

bPTV Volume (cc)

85.1 (11.0–328.5)

81.4 (28.3–285.3)

0.94

PTV Volume (cc)

359.3 (128.9–779.1)

370.8 (193.9–877.5)

0.18

Brain Volume (cc)

1301.5 (1022.2–1849.0)

1326.9 (1016.0–1658.6)

0.23

# Beams

<0.001

 2

0

38

 

 3

0

7

 5

43

0

 6

2

0

# Couch Angles

<0.001

 1

0

39

 

 2

0

6

 4

45

0

Multileaf Collimator

0.02

 High Definition

33

42

 

 Standard

12

3

# Monitor Units

347 (285–487)

453 (274–665)

<0.001

Treatment Time

15.0 (7.7–21)

10.0 (6.3–15.3)

<0.001

  1. IMRT intensity modulated radiation therapy, VMAT volumetric arc therapy, bPTV boost planning target volume prescribed to 60 Gy, PTV planning target volume prescribed to 50 Gy
  2. *From Fisher’s exact test or Wilcoxon-Mann–Whitney rank sum analysis