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Table 2 Univariate and multivariate analysis of risk factors for radiation induced rib fracture

From: Predictors of chest wall toxicity after stereotactic ablative radiotherapy using real-time tumor tracking for lung tumors

  

Rib fracture

p-value

Variables

 

No

Yes

Univariate

Multivariate

Sex

Male

26

4

0.493

NS

 

Female

15

4

  

Age

≤65

18

3

0.636

NS

 

>65

23

5

  

Tumor location

Upper lobe

15

4

0.086

NS

 

Lower lobea

26

4

  

Multiple treatment

No

24

5

0.759

NS

 

Yes

17

3

  

DM

No

32

6

0.581

NS

 

Yes

9

2

  

COPD

No

35

5

0.061

NS

 

Yes

6

3

  

GTV volume

≤17 cc

33

4

0.097

NS

 

>17 cc

8

4

  

Rib-tumor distance

≤0.4 cm

21

8

0.035

_

 

>0.4 cm

20

0

  

D4.6cc

≤140 Gy, EQD2

27

1

0.001

0.009

 

>140 Gy, EQD2

21

7

  

V160

≤3.2 cc

27

0

0.000

_

 

>3.2 cc

22

8

  
  1. aincludes middle lobe in case of right lung
  2. DM diabetes mellitus, COPD chronic obstructive pulmonary disease, GTV gross tumor volume