Variables | Grade 2 ≥ Radiation Pneumonitis | Univariate Analysis | Multivariate Analysis | ||||
---|---|---|---|---|---|---|---|
n | Rates (%) | OR (95%CI) | p-value | OR (95%CI) | p-value | ||
T stage | T1a + T1b | 189 | 13.2 | Reference | - | Reference | - |
T2a + T2b | 86 | 15.1 | 1.168 (0.552–2.377) | 0.6760 | 1.381 (0.590–3.121) | 0.4485 | |
Histology | Adenocarcinoma | 177 | 15.3 | 1.553 (0.698–3.817) | 0.2902 | 1.492 (0.608–3.963) | 0.3896 |
SCC | 77 | 10.4 | Reference | - | Reference | - | |
Gender | Female | 69 | 15.9 | 1.257 (0.567–2.632) | 0.5600 | 1.298 (0.525–3.099) | 0.5643 |
Male | 206 | 13.1 | Reference | - | Reference | - | |
Location | Upper and Middle | 160 | 11.3 | Reference | - | Reference | - |
Lower | 115 | 17.4 | 1.661 (0.834–3.329) | 0.1481 | 2.281 (1.042–5.063) | 0.0392 | |
BED (10) IC (Gy) | ≥90 | 256 | 14.5 | NE (1.593–NE) | 0.0154 | NE (1.803–NE) | 0.0118 |
<90 | 19 | 0.0 | Reference | - | Reference | - | |
Margins from GTV to PTV (mm) | ≥10 | 151 | 21.2 | 6.185 (2.530–18.579) | <0.0001 | 6.479 (2.558–19.988) | <0.0001 |
<10 | 120 | 4.2 | Reference | - | Reference | - |