Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors

Table 2 The utilization of PWI-derived metrics in brain tumor treatment course

Utilities	DSC					DCE	ASL
Utilities	rCBV	rCBF	rMTT	K^trans	K^trans/rK^trans	riAUC	rCBF
Prognosis	[67]	[5]			[67]		[5]
Invasion	[58]		[59]	[59]
RT treatment planning	[55–57]
Response to treatment	[63]						[66]
Progression vs. pseudo-progression	[63]
Distinguishing tumor recurrence from treatment effect	[64, 65]				[65]	[65]
Re-irradiation treatment planning	[68–70]

DSC dynamic susceptibility-weighted contrast-enhanced perfusion MRI, DCE dynamic contrast-enhanced MRI, ASL arterial spin-labeling, rCBV relative cerebral blood volume, rCBF relative cerebral blood flow, rMTT relative mean transit time, K ^trans transfer constant, rK ^trans relative K^trans, riAUC initial area under the concentration curve

ISSN: 1748-717X