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Table 5 Analysis of dose volume histograms of IMRT and PSPT plans

From: Establishing the feasibility of the dosimetric compliance criteria of RTOG 1308: phase III randomized trial comparing overall survival after photon versus proton radiochemotherapy for inoperable stage II-IIIB NSCLC

Structure

 

Photon IMRT

Proton PSPT

Median

Mean ± SE

Median

Mean ± SE

PTV

% of PTV covered by RX

95

95

95

95

PTV minimum

57.0

56.7 ± 1.5

55.0

55.5 ± 1.4

PTV maximum

81.3

81.6. ± 0.7

79.9

80.9 ± 0.9

Normal lung (total lungs – GTV)

Lung V5

42.6

47.2 ± 2.6

35.3

34.4. ± 1.6

Lung V20

27.9

28.1 ± 1.6

29.32

27.6 ± 1.5

Mean Lung dose

18.4

17.8 ± 0.9.

18.3

16.4. ± 0.9.

Spinal cord

Spinal Cord maximum dose

43.8

43.5 ± 1.4

37.9

31.7 ± 3.1

Heart

V5

39.4

47 ± 6

16.6

19. ± 3

V30

15.7

19 ± 4

9.7

11 ± 2

V45

7.7

12.1 ± 2.7

7.4

7.8 ± 1.5

V50

5.4

9.8. ± 2.3

6.5.

7.1 ± 1.4

V60

2.6

6.2 ± 1.5

4.2

6.7 ± 1.2

V66

1.8

4.2 ± 1

2.9

4.7 ± 1.1

Heart mean dose

12.7

14.9 ± 2.4

6.7

7.7. ±1.4

Maximum Dose

78

69.3. ± 4.5

76.4

68.5. ± 4.4.

Esophagus

Mean dose

20.1

22.7 ± 1.9

21.2

23 ± 2

Maximum dose

76.2

73.2 ± 2.5

74.1

71. ± 3

Brachial Plexus

V70

0

0.50

0

1.0

V74

0

0.27

0

0.10

V75

0

0.18

0

0.11

  1. SE standard error
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Radiation Oncology

ISSN: 1748-717X

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