Table 4 Multivariate analysis of volumetric parameter cut-off values compared to survival outcomes

Sex (Male vs. Female)

NS

NS

NS

Histology (SqCC vs. Others)

NS

1.455 (0.983–2.155)

0.061

NS

T stage (T1-T2 vs. T3-T4)

NS

NS

NS

N stage (N0-N2 vs. N3)

NS

NS

NS

Stage (IIIA vs. IIIB)

NS

NS

NS

GTV_pre (≤ 50 cm³ vs. > 50 cm³)

2.926 (1.495–5.726)

0.002

2.001 (1.159–3.454)

0.013

2.763 (1.552–4.919)

0.001

GTV_post (≤ 20 cm³ vs. > 20 cm³)

NS

1.467 (0.947–2.273)

0.086

NS

VRR (≤ 50% vs. > 50%)

NS

NS

1.895 (0.937–3.832)

0.075