From: Clinical outcomes and toxicity of proton beam therapy for advanced cholangiocarcinoma
N | % | |
---|---|---|
Total dose (Gy (RBE)) | ||
50.6–60 | 7 | 43 |
61.6–70 | 11 | 21 |
70.4–80 | 10 | 11 |
Dose/fraction (Gy (RBE)) | ||
2.0 | 2 | 7 |
2.2 | 20 | 71 |
2.4 | 5 | 18 |
3.2 | 1 | 4 |
BED10 (α/β = 10) (Gy) | ||
61.7–69.5 | 6 | 21 |
72.5–75.1 | 10 | 36 |
83.2–89.3 | 10 | 36 |
91.3–105.6 | 2 | 7 |
BED3 (α/β = 3) (Gy) | ||
87.7–98.8 | 6 | 21 |
103.0–108.0 | 10 | 36 |
116.7–118.2 | 3 | 11 |
122.2–165.3 | 9 | 32 |
History of chemotherapy | ||
None | 18 | 64 |
Completed | 10 | 36 |
Follow-up chemotherapy | ||
None | 13 | 50 |
Concurrent | 3 | 11 |
Adjuvant | 15 | 50 |
Regimen | ||
S-1 | 5 | 18 |
GEM | 7 | 25 |
S-1 + GEM | 2 | 7 |
GEM + CDDP | 1 | 4 |