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Table 2 Prostate volumes in descending order as segmented on the treatment planning CT and on the MR images before radiotherapy (MRI baseline ), in the middle of the treatment (MRI mid ) and at the end of treatment (MRI end )

From: Change in prostate volume during extreme hypo-fractionation analysed with MRI

Pat #

CT

MRIbaseline

MRImid

MRIend

 

Abs. vol. (cm3)

Rel. vol.

Abs. vol. (cm3)

Abs. vol. (cm3)

Rel. vol.

Abs. vol. (cm3)

Rel. vol.

1

35.3

1.579

22.4

26.7

1.191

27.2

1.217

2

44.5

1.369

32.5

38.6

1.187

34.9

1.074

3

33.8

0.999

33.9

39.0

1.151

33.1

0.976

4

47.8

1.105

43.3

47.5

1.098

46.2

1.067

5

45.8

1.054

43.4

48.9

1.126

48.7

1.122

6

64.8

1.455

44.5

53.3

1.198

44.1

0.991

7

71.6

1.597

44.8

49.8

1.112

46.6

1.040

8

43.5

0.906

48.0

48.7

1.015

48.0

1.000

9

79.4

1.648

48.2

55.5

1.152

54.4

1.129

10

73.0

1.511

48.4

48.9

1.011

50.1

1.037

11

59.4

1.102

53.9

60.8

1.128

55.2

1.023

12

57.0

1.037

54.9

65.3

1.189

64.4

1.172

13

--*

--*

57.2

66.6

1.166

62.2

1.089

14

83.8

1.196

70.1

88.7

1.265

78.0

1.112

15

99.0

1.347

73.5

80.0

1.088

74.1

1.008

16

79.4

1.066

74.5

95.5

1.282

96.2

1.291

17

96.5

1.145

84.3

96.8

1.148

--

--

18

105.8

1.242

85.2

96.3

1.131

101.4

1.190

19

106.2

1.021

104.0

116.8

1.123

115.6

1.112

20

153.7

1.045

147.1

155.0

1.054

152.9

1.040

Mean

72.7

1.233

60.7

68.9

1.141

64.9

1.089

SD

30.4

0.232

28.7

31.3

0.070

31.9

0.084

p-value

0.0001

0.0004

---

<0.0001

<0.0001

0.0008

0.0002

  1. Relative volumes and p-values are in relation to MRIbaseline.
  2. *Prostate was not segmented on CT as the patient had a hip prosthesis.
  3. Missing data, MRI not performed.
  4. Paired t-test.