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Table 4 Nonhematologic toxicity

From: Dose escalation of accelerated hypofractionated three-dimensional conformal radiotherapy (at 3 Gy/fraction) with concurrent vinorelbine and carboplatin chemotherapy in unresectable stage III non-small-cell lung cancer: a phase I trial

Toxicity

66 Gy

69 Gy

72 Gy

Total

Case

Case

Case

Case (%)

Radiation pneumonia

   

10(76.9)

I

1

2

1

 

II

1

2

2

 

III

0

0

1

 

Radiation oesophagitis

   

11(84.6)

I

1

2

1

 

II

1

3

1

 

III

0

0

2

 

Radiation dermatitis

   

9(69.2)

I

1

3

3

 

II

0

1

1

 

Nausea

   

12(92.3)

I

1

2

1

 

II

1

2

1

 

III

1

1

2

 

Vomiting

   

8(61.5)

I

1

1

2

 

II

1

1

1

 

III

0

1

0

 

Anorexia

   

12(92.3)

I

1

1

1

 

II

2

2

1

 

III

0

2

2

 

Fatigue

   

11(84.6)

I

0

3

1

 

II

1

2

2

 

III

1

0

1

 

ALTI

0

1

2

3(23.1)

ASTI

1

0

2

3(23.1)

Cr I

1

0

1

2(15.4)

BIL I

0

1

0

1(7.7)

  1. ALT: alanine aminotransferase; AST: aspartate aminotransferase; Cr: serum creatinine; BIL: bilirubin.
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Radiation Oncology

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