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Table 2 Clinical parameters in patients with or without an increase in Child-Pugh score ≥ 2

From: Dosimetric parameter predicting the deterioration of hepatic function after helical tomotherapy in patients with unresectable locally advanced hepatocellular carcinoma

 

Without (n = 40)

With (n = 32)

pvalue

Gender

  

0.584

   Male

31

23

   Female

9

9

Age (years)

  

0.231

   median

62

59

   range

21-80

41-80

ECOG PS

  

0.910

   0

13

10

   1

27

22

Hepatitis

  

0.109

   No

0

2

   Yes

40

30

AFP (IU/mL)

  

0.094

   <400

30

18

   ≥400

10

14

LC

  

0.228

   No

11

5

   Yes

29

27

PVTT

  

*0.037

   No

21

9

   Yes

19

23

CP class

  

*0.006

   A

35

19

   B

5

13

AJCC stage

  

*0.021

   II

11

1

   III

26

27

   IVA

3

4

Previous treatment

  

0.374

   No

5

2

   Yes

35

30

Treatment after RT

  

0.394

   No

19

12

   Yes

21

20

  1. Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status; AFP alpha-fetoprotein; LC liver cirrhosis; PVTT portal vein tumor thrombosis; CP class Child-Pugh class; AJCC American Joint Committee on Cancer; RT radiotherapy.
  2. *Significant parameters in univariate analysis.
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Radiation Oncology

ISSN: 1748-717X

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