Figure 4
From: Increased Artemis levels confer radioresistance to both high and low LET radiation exposures
Artemis over-expression facilitates repair and passage through the G2/M checkpoint. Flow cytometry of propidium iodine stained cells reveals cell cycle kinetics following various doses of X-ray, Fe ion, or Ti ion exposure. Cell cycle profiles for wild type HEK293 cells are shown in white and cells over-expressing Artemis (293Art) are Black. Peaks corresponding to location of G1 and G2 cells are indicated at the base of the figure, with dose and radiation quality noted on the Y and X axis respectively.