Acute gastrointestinal and genitourinary toxicity of image-guided intensity modulated radiation therapy for prostate cancer using a daily water-filled endorectal balloon

Table 4 Bladder, Bladder Wall, Proximal Bladder, and Proximal Bladder Wall DVH Analysis and Univariate Associations with Grade ≥ 2 GU Toxicities

	Bladder		In-field Bladder		Bladder Wall		In-field Bladder Wall
	Mean ± SD	P value	Mean ± SD	P value	Mean ± SD	P value	Mean ± SD	P value
Volume (cm³)	246 ± 167	0.31	101.5 ± 42.9	0.34	55.2 ± 24.6	0.44	25.9 ± 8.1	0.65
D_min (Gy)	3.6 ± 4.7	0.92	13.0 ± 5.9	0.55	3.6 ± 4.7	0.94	12.5 ± 6.6	0.21
D_max (Gy)	82.5 ± 1.6	0.26	82.5 ± 1.6	0.26	82.4 ± 1.6	0.24	82.4 ± 1.6	0.24
D_mean (Gy)	31.0 ± 11.2	0.64	50.4 ± 5.8	0.16	33.2 ± 10.6	0.72	54.9 ± 5.7	0.23
D_median (Gy)	23.1 ± 15.2	0.62	48.6 ± 8.1	0.16	23.4 ± 16.2	0.60	56.0 ± 9.9	0.20
V₁₀ (%)	66.6 ± 25.1	0.66	99.2 ± 3.2	0.11	64.6 ± 22.8	0.61	99.0 ± 2.9	0.14
V₂₀ (%)	57.1 ± 24.1	0.55	94.6 ± 7.6	0.03	56.2 ± 20.9	0.66	94.5 ± 6.5	0.06
V₃₀ (%)	46.4 ± 20.4	0.65	81.3 ± 11.1	0.20	47.1 ± 17.5	0.84	82.6 ± 9.5	0.37
V₄₀ (%)	35.4 ± 15.0	0.65	64.6 ± 11.9	0.48	38.7 ± 13.6	0.86	69.7 ± 10.5	0.57
V₅₀ (%)	25.4 ± 10.1	0.40	48.0 ± 11.4	0.27	30.5 ± 10.4	0.61	56.1 ± 10.9	0.30
V₆₀ (%)	17.9 ± 7.3	0.46	34.6 ± 10.0	0.32	24.2 ± 8.5	0.63	45.4 ± 10.6	0.34
V₆₅ (%)	15.1 ± 6.3	0.41	29.4 ± 9.2	0.26	21.9 ± 7.8	0.59	41.3 ± 10.1	0.30
V₇₀ (%)	12.4 ± 5.4	0.38	24.6 ± 8.3	0.23	19.7 ± 7.1	0.56	37.5 ± 9.6	0.29
V₇₅ (%)	9.5 ± 4.4	0.32	18.9 ± 7.4	0.22	16.9 ± 6.4	0.45	32.6 ± 9.3	0.24
V_79.2 (%)	4.7 ± 3.0	0.45	9.9 ± 6.5	0.48	10.2 ± 5.3	0.52	20.6 ± 10.4	0.45

Abbreviations: DVH = dose volume histogram; D_min = minimum dose; D_median = median dose; D_mean = mean dose; D_max = maximum dose; V₁₀, V₂₀, V₃₀, V₄₀, V_50, V₆₀, V₆₅, V₇₀, V_75, V_79.2 = volume receiving 10 Gy, 20 Gy, 30 Gy, 40 Gy, 50 Gy, 60 Gy, 65 Gy, 70 Gy, 75 Gy, 79.2 Gy, respectively.
Note: The results are presented as mean ± standard deviation.

ISSN: 1748-717X